While pemigatinib exerts its therapeutic effect, it may cause different types and degrees of side effects due to individual differences in physical condition. Users should monitor for these side effects and consult a doctor promptly.
Serious Side Effects of Pemigatinib
Although not all side effects will occur, medical intervention may be required if they do. If any of the following side effects occur while taking pemigatinib, seek immediate medical attention:
Common Serious Side Effects
Urinary System: Bladder pain, hematuria or cloudy urine, decreased urination, difficulty urinating, burning or painful urination, urinary frequency (frequent urge to urinate), lower back or flank pain.
Digestive System: Diarrhea, stomach cramps.
Cardiovascular System: Increased heart rate, irregular heartbeat.
Nervous System: Confusion, dizziness, vertigo or syncope, muscle cramps (occurring in the hands, arms, feet, legs or face), numbness and tingling around the mouth, fingertips or feet, seizures, tremors.
Eyes: Dry eyes, red eyes, eye irritation or pain, flashes of light or sparks when seeing objects, floaters or curtain-like obstructions in the field of vision, sunken eyes.
Skin, Hair, and Nails: Changes in nails (fingernails or toenails), loose fingernails, redness or pain around fingernails, pale skin, wrinkled skin, abnormal bleeding or bruising.
Musculoskeletal System: Bone pain.
Systemic and Metabolic: Dry mouth, decreased appetite, altered mood or mental state, difficulty breathing, rapid breathing, thirst, unusual fatigue or weakness, unusual weight loss, swelling of hands, ankles, feet, or lower legs.
Less common serious side effects: Pain or swelling in the arms or legs without external injury.
Other Side Effects of Pemitinib
Pemitinib may cause some side effects that usually do not require medical attention; these side effects may disappear on their own as the body gradually adapts to the drug during treatment. If any of the following side effects persist, bother you, or you have any questions about them, please consult a healthcare professional:
Other Common Side Effects
Excessive stomach acid or acid reflux, belching, swelling (swelling of the face, arms, hands, calves, or feet, or abdominal bloating), altered taste, constipation, difficulty moving, dry skin, hair loss, heartburn, indigestion, loss of taste, nausea, joint pain, rapid weight gain, skin redness, swelling or pain of the skin, peeling skin on the hands and feet, stomach upset, stomach discomfort or pain, swelling or inflammation of the mouth, skin ulcers, vomiting.
