No, you should avoid foods or drinks that contain grapefruit while you are being treated with Rinvoq. Consuming grapefruit or the juice may increase the risk of side effects because blood levels of Rinvoq may increase. Check the labels of foods you eat or drink to see if grapefruit is an ingredient.
Rinvoq is broken down in the body for excretion (or metabolized) by an enzyme called CYP3A4. Grapefruit is considered a strong CYP3A4 inhibitor and may interfere with the metabolism and excretion of Rinvoq. This can increase blood levels and side effects from the drug.
